CV, Awards & Honours

Curriculum Vitae

Neurovascular biologist with over 16 years of experience across academia and industry.

Download the full CV (PDF) All 16 publications LinkedIn

Experience

Appointments

2025 – present Current

Senior Scientist and Project Leader, Bioinformatics

ProQR Therapeutics

Leiden, The Netherlands

Bioinformatics strategy for RNA-editing therapeutic programs in liver and CNS disease.

Data-driven CNS and liver disease biology: generate biological insights for RNA-editing therapeutic programs
Mechanistic interpretation of therapeutic response: integrate transcriptomic, target-engagement and off-target datasets
Scientific leadership and mentoring: lead and mentor junior scientists in biological interpretation of complex datasets
RNA-seq experimental design for high-throughput screening, model characterization and lead selection
Support CNS discovery programs in epilepsy, Rett syndrome and Alzheimer's disease by prioritizing oligonucleotide candidates
Apply pathway, network and statistical analyses to guide cross-functional decisions across biology, genomics, pathology and toxicology
Develop reproducible analytical workflows in R, Python, Linux/HPC and Nextflow
Implement FAIR data-management principles and experimental protocol tracking in Dotmatics
Contributed pharmacodynamic and biological data analyses supporting the IND application for AX-810 in cholestatic disease

2025 – present Current

Guest Scientist

University of Münster

Münster, Germany

Continued manuscript development and biological interpretation of neurovascular transcriptomics datasets.

Neurovascular transcriptomics: single-cell, spatial and translational datasets focused on CNS disease mechanisms
Doctoral mentoring in neurovascular disease biology, omics analysis, data visualization, hypothesis development and manuscript preparation

2017 – 2025

Postdoctoral Researcher

University of Münster

Münster, Germany

Neurovascular unit, cerebral small vessel disease, stroke and vascular basement membrane biology.

Co-led the EU Horizon 2020 SVDs@target consortium (12 laboratories across 7 countries) and DFG-funded stroke/obesity collaborations with partners in Germany and China
Established imaging, histopathology, functional physiology and omics workflows for cerebral small vessel disease, stroke and neurovascular unit dysfunction
Demonstrated that Notch3 mutant and hypertensive BPH/2J mice recapitulate key human small vessel disease features
Performed MRI–histopathology correlation studies on human autopsy tissue to define white matter lesion pathology
Elucidated roles of vascular basement membrane laminins in cerebral microvessel functional zonation and stroke outcome
Optimized single-cell dissociation and analysis workflows for 10x Genomics and BD Rhapsody platforms
Reanalyzed public single-cell RNA-seq datasets to generate experimentally validated mechanistic hypotheses
Established cerebral blood-flow measurement by laser Doppler flowmetry; certified for rodent surgery under EU regulations
Co-supervised two doctoral theses and one master's thesis; taught image analysis and FACS/immunology practicals

2012 – 2017

Doctoral Researcher

University of Bonn

Bonn, Germany

Molecular mechanisms of astrocyte dysfunction and astrocytic uncoupling in epilepsy.

Investigated astrocytic uncoupling in epilepsy using human tissue, mouse models, biochemical assays, high-resolution microscopy and proteomics
Automated cellular characterization in human brain tissue; identified pathological protein-distribution patterns in epilepsy specimens
Purified connexin43 and identified post-seizure phosphorylation sites by mass spectrometry
Visualized gap-junction reorganization in human brain samples using expansion microscopy
Received the NRW International Graduate School BIOTECH PHARMA fellowship; completed the doctorate magna cum laude

2010 – 2012

Junior Scientist

Dr. Reddy's Laboratories

Hyderabad, India

Translational pharmacology and formulation-development support, Centre of Excellence — Bio Studies.

Supported novel drug-formulation development through the Centre of Excellence – Bio Studies
Instituted statistical models to predict formulation performance in vivo
Performed pharmacokinetic modeling for novel formulations
Collaborated across formulation, pharmacokinetics and translational development teams to deliver bioequivalence studies

Education

Degrees

2012–2017

PhD in Neuroscience

University of Bonn

Germany

Dissertation: molecular mechanisms of astrocyte dysfunction in epilepsy. Graduated magna cum laude; NRW International Graduate School BIOTECH PHARMA fellow.

2008–2010

M.S. in Pharmacology

National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar

India

Thesis: Role of endothelin receptors in stroke.

2004–2008

Bachelor of Pharmacy

Government College of Pharmacy, Aurangabad

India

Training in drug discovery, drug development, pharmacology and pharmaceutical sciences.

Honours

Awards & fellowships

2023 Best Presentation Award (first prize) Symposium “Signal Transduction at the BBB”, Uppsala, Sweden

2021 Young Pharmacologist Award NIPER, Raebareli, India

2012 NRW International Graduate School BIOTECH PHARMA Fellowship University of Bonn

Certifications

Licences & training

2023 Certificate for Performing Surgical Procedures on Anesthetized Mice Animal Protection Unit, Veterinary Office, University of Münster

2023 AI in Medical Imaging University of Münster

2021 AI Theory and Techniques for Interdisciplinary Research University of Münster

2017 General Animal Experimentation Certificate University of Münster

References

Available on request

Referees from the University of Münster, the University of Bonn and NIPER can be provided on request — please get in touch.

Request references